Synthesis of Natural Rubrolides B, I, K, L, M, O and Analogues

C O M P U T a T I O N a L B I O L O G Y

33 T he prevailing method of determining the sequence of a long DNA segment is the shotgun sequencing approach, in which a random sampling of short fragment sequences is acquired and then assembled by a computer program to infer the sampled segment's sequence. In the early 1980s, such segments were typically on the order of 5,000 to 10,000 base pairs (5 to 10 kbp). By 1990, this method was sequ...

M Y O H E M O G L O B I N U R I a a Sxudy of "l'~-~ Renal Clearance of Myohemoolobin in Dogs*

The observation that hemoglobin extracted from muscle was excreted by the kidneys much more rapidly than blood hemoglobin was perhaps the first indication that these two substances are different (4, 7). Since the purification and crystallization of myohemoglobin by Theorell (13) in 1932 many of its chemical and physical properties have been elucidated. Also ideas concerning renal function have ...

C O M P U T a T I O N a N D M U L T I P L I C I T Y O F E Q U I L I B R I A

H E M O G L O B I N Absorption by the Cells of the P R O X I M a L Convoluted Tubule in Mouse K I D N E Y

The formation of protein absorption droplets in the cells of the proximal convolution was studied in mouse kidney. Ox hemoglobin was administered in t raper i toneal ly and kidney specimens were collected at intervals of 30 minutes to 4 days after injection. In the lumen of the nephron, hemoglobin was concentrated to an opaque mass whose relations with the brush border and the epithelium could ...

M.rtsr-ldper Control Strategy to Robotic Syatms L T M C K B an O B K T Smbjsct To

Abotrut. A hierarchical control strategy is developed in thispaper for robotic systems (multiple robots systems) holding a rig. id body to track a given motion in the presence o f enviromrntal con. draintl. New mathematical formulation to the enviromental con. dralnts is introduced which is simple enough in many caws. The control b constructed following a master-helper control scheme in which t...